Immunization information systems, or registries, have been around for more than 20 years but they are now focused on interoperability with electronic health records, creating a comprehensive immunization database to better track vaccinations.

To be valuable, immunization information systems must receive and contain data that is timely, accurate, and complete. Run by state, city or regional public health agencies, these population-based systems include all vaccination doses administered by participating providers to people within a given area and consolidate vaccinations administered by different providers into a single electronic record. Depending on state laws, schools and health plans also participate in these systems.

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