The National Institutes of Health is collaborating with the Defense Advanced Research Projects Agency and Food and Drug Administration to create miniature 3D models of living organs and tissues on microchips to test drug safety and efficacy more accurately and less costly than current methods.
The aim of these models is to predict whether a candidate drug, vaccine or biologic agent is safe or toxic in humans. According to NIH, more than 30 percent of promising medications have failed in human clinical trials because they are determined to be toxic despite promising pre-clinical studies in animal models. The problem with traditional animal models is that they do not accurately mimic human physiology. However, these organs-on-chips could potentially eliminate toxic and/or ineffective drugs earlier development, thereby saving time and money.
Register or login for access to this item and much more
All Health Data Management content is archived after seven days.
Community members receive:
- All recent and archived articles
- Conference offers and updates
- A full menu of enewsletter options
- Web seminars, white papers, ebooks
Already have an account? Log In
Don't have an account? Register for Free Unlimited Access