Medical device company CareFusion Corp. has introduced a software algorithm to automatically control the oxygen level in newborns needing mechanical ventilation.

The Closed Loop Controller of Inspired Oxygen system, or CLiO2T, is an enhancement to the San Diego-based company's AVEAT ventilator. The system processes blood oxygen saturation levels using a computer algorithm that anticipates trends and modifies the amount of oxygen delivered, second-by-second if necessary. Oxygen levels that are too high or low can cause lung and vision damage in premature babies, says Steven Donn, M.D., a professor of pediatrics at the University of Michigan Health System, which was a clinical trials site.

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