It is simple in theory: Patients take their drugs on time and in the dosages prescribed by their physicians. However, in practice, medication non-adherence continues to be a serious problem in the United States, with a patient dying every 90 minutes due to an accidental overdose or missed dose of a prescription drug, according the Express Scripts 2013 Drug Trend Report. It's also costly for the U.S. health system: the United States wastes $317.4 billion annually on unnecessary medical costs that could be avoided by eliminating medication non-adherence, according the same report.

A 2013 poll of U.S. adults showed that nearly two-thirds of Americans who take prescription medications do not take their medication as prescribed. The poll was conducted by Greenberg Quinlan Rosner Research and Public Opinion Strategies for the Council for Affordable Health Coverage.

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