Researchers at Johns Hopkins Medicine are borrowing ideas from evolutionary game theory to learn how cells cooperate within a tumor to gather energy. Their experiments, they say, could identify the ideal time to disrupt metastatic cancer cell cooperation and make a tumor more vulnerable to anti-cancer drugs.

Game theory is a mathematical study of strategic decision-making, and has been widely used to predict conflict and cooperation between individuals and even nations, but increasingly is applied to forecasting cell-to-cell interactions in biology with an ecological perspective.

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